BDBM50398609 CHEMBL2141296::IXAZOMIB CITRATE::Ixazomib::MLN2238::NINLARO

SMILES CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B(O)O

InChI Key InChIKey=MXAYKZJJDUDWDS-LBPRGKRZSA-N

Data  20 IC50  1 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398609   

TargetProteasome subunit beta type-9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50398609(CHEMBL2141296 | IXAZOMIB CITRATE | Ixazomib | MLN2...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human 20S immunoproteasome beta-1i subunit using (Ac-PAL)2R110 as substrate preincubated for 2 hrs followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails PubMed